Benzenebutanamine → 2-Chloro-6-(4-phenylbutylamino)-9-cyclopentylpurine

HRID 2227308Notes

Reaction equation

HRID 2227308 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[C:17]1([CH2:23][CH2:24][CH2:25][CH2:26][NH2:27])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([NH:27][CH2:26][CH2:25][CH2:24][CH2:23][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:3]=1

Participants

4

Reactant 2

HCID 83242BenzenebutanamineHCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 184733932-Chloro-6-(4-phenylbutylamino)-9-cyclopentylpurine

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-(4-phenylbutylamino)-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 4-phenylbutylamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-99b27e52479547a78ea3c17f8e20d386
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

Loading…