3-Phenylpropylamine → 2-Chloro-6-[3-(phenyl)propylamino]-9-cyclopentylpurine

HRID 2227310Notes

Reaction equation

HRID 2227310 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[NH2:17][CH2:18][CH2:19][CH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([NH:17][CH2:18][CH2:19][CH2:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[N:3]=1

Participants

4

Reactant 2

HCID 162593-PhenylpropylamineHCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 184733212-Chloro-6-[3-(phenyl)propylamino]-9-cyclopentylpurine

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-[3-(phenyl)propylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 3-aminopropylbenzene, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-9106e37ea39a4effb222074d387d7ae4
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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