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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2227318Generated: October 26, 2026

Cyclopropanemethanamine → 2-Chloro-6-[(cyclopropyl)methylamino]-9-(2-propyl)purine

https://huagongshe.com/reaction/2227318

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanemethanamineHCID 75646—
Reactant2,6-dichloro-9-(propan-2-yl)-9H-purineHCID 11218490—
SolventTriethylamineHCID 8471—
Product2-Chloro-6-[(cyclopropyl)methylamino]-9-(2-propyl)purineHCID 86758300—

Reaction Steps

2-Chloro-6-[(cyclopropyl)methylamino]-9-(2-propyl)purine is prepared from 2,6-dichloro-9-(2-propyl)purine (See Example 15 for preparation), cyclopropylmethylamine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06413974B1
Source datasetuspto-grants-2002_07
ORD IDord-02e6745b8d3848879f7cde803d1183b8
Source noteuspto-grants-2002_07