Cyclopropanemethanamine → HCID 18473444, compound

HRID 2227320Notes

Reaction equation

HRID 2227320 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[NH2:17][CH2:18][CH:19]1[CH2:21][CH2:20]1>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([NH:17][CH2:18][CH:19]2[CH2:21][CH2:20]2)[N:3]=1

Participants

4

Reactant 2

HCID 75646CyclopropanemethanamineHCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 18473444HCID 18473444, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-[(cyclopropyl)methylamino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, aminomethylcyclopropane, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-c5c6f4904f6a4159b58f91d2212a061a
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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