Phenelzine → 2-Chloro-6-[2-phenethylhydrazino]-9-cyclopentylpurine

HRID 2227321Notes

Reaction equation

HRID 2227321 reaction equation
[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4](Cl)[N:3]=1.[C:17]1([CH2:23][CH2:24][NH:25][NH2:26])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C(N(CC)CC)C>[Cl:1][C:2]1[N:10]=[C:9]2[C:5]([N:6]=[CH:7][N:8]2[CH:11]2[CH2:15][CH2:14][CH2:13][CH2:12]2)=[C:4]([NH:26][NH:25][CH2:24][CH2:23][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[N:3]=1

Participants

4

Reactant 2

HCID 3675PhenelzineHCID 108011162,6-dichloro-9-cyclopentyl-9H-purine

Product 1

HCID 184733812-Chloro-6-[2-phenethylhydrazino]-9-cyclopentylpurine

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Chloro-6-[2-phenethylhydrazino]-9-cyclopentylpurine is prepared from 2,6-dichloro-9-cyclopentylpurine, 2-phenylethylhydrazine, and triethylamine essentially as described above in Example 1, Scheme A, step b.

Sources & evidence

ORD record
ord-d4e97df9fbb84fbfb0cc2cdc94cecae6
Source dataset
uspto-grants-2002_07
Patent number
US06413974B1

Reaction notes

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