反应详情

1 g (2.77 mmol) of 3-(5-(1,3-dioxan-2-yl)furan-2-yl)-1-(4-picolyl)indazole is dissolved in 10 ml of acetone, and 20 ml of 50 per cent strength acetic acid are added. The mixture is boiled for 1 hour, introduced into water and extracted with ethyl acetate and the organic phase is dried with sodium sulphate and evaporated in vacuo to give 0.8 g (95.3% of theory) of an oil. Rf (SiO2, ethyl acetate): 0.25

1. extractionextracted with ethyl acetate
2. dry with materialthe organic phase is dried with sodium sulphate
3. customevaporated in vacuo
4. customto give 0.8 g (95.3% of theory) of an oil