HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Dodecyl N,N-dimethylalaninate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 1-Dodecanol | HCID 8193 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 13010786 | HCID 13010786 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Dodecyl N,N-dimethylalaninate | HCID 3025823 | — |
Reaction Steps
DDAIP was prepared by transesterification of ethyl 2-(N,N-dimethylamino)-propionate obtained from Varsal Instruments Inc. (Warminster, Pa.). Specifically, a mixture ethyl 2-(N,N-dimethylamino)-propionate, 1-dodecanol, and sodium methoxide predissolved in toluene was refluxed for about 2 hours. As ethanol formed, it was removed by azeotropic distillation. After about 2 hours of refluxing, the remaining reaction product was filtered to remove solids.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06414028B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-19c73369a2e24b6394f152a54b63f3ef |
| Source note | uspto-grants-2002_07 |