HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 1-Bromo-3,5-di-tert-butylbenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 3,5-Di-tert-butylphenol | HCID 70825 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-Bromo-3,5-di-tert-butylbenzene | HCID 620136 | — |
Reaction Steps
After bromine addition, the ice bath was removed. 124 g of 3,5-di-tertbutylphenol (601 mmol) and 140 mL acetonitrile were added in one portion. The orange/white suspension converted into an orange solution upon heating. The mechanical stirrer was replaced by an egg-shape stir bar. The solution was stirred at gentle reflux temperature for three hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06414095B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-8559be7d3f3f4987a482fce4cb49966d |
| Source note | uspto-grants-2002_07 |