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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 222775Generated: October 29, 2026

3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OL → HCID 57453924, compound

https://huagongshe.com/reaction/222775

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OLHCID 10082081—
Reactant4-(6-Chloropyrazin-2-yl)morpholineHCID 26370209—
ProductHCID 57453924HCID 57453924—

Reaction Steps

Example (E288) was prepared from 3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol (E3) and 4-(6-chloro-2-pyrazinyl)morpholine [Zagulyaeva, O. A., J. Org. Chem. USSR, EN, 14; 1978; 377-380] using an analogous method to that described for Example 242 (E242); MS (ES+) m/e 381 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08207331B2
Source datasetuspto-grants-2012_06
ORD IDord-3c0b3de491d749bfaa43a01022126f11
Source noteuspto-grants-2012_06