HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dichloroaniline → 2-(3,5-Dichlorophenylamino)nicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dichloroaniline | HCID 12281 | — |
| Reactant | 2-Chloronicotinic acid | HCID 76258 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-(3,5-Dichlorophenylamino)nicotinic acid | HCID 12627619 | 97.9% |
Reaction Steps
2-Chloronicotinic acid (10 g) was combined with 3,5-dichloroaniline (15 g) in 150 mL acetic acid and heated at reflux for 4 hr. Upon cooling, a white solid formed which was collected by filtration, washed with acetic acid, water, and dried to give 17.6 g of 2-(3,5-dichlorophenylamino)nicotinic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06414153B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-49906059e42f44d1a88a703f71e97cdc |
| Source note | uspto-grants-2002_07 |