反应详情

2-Chloronicotinic acid (10 g) was combined with 3,5-dichloroaniline (15 g) in 150 mL acetic acid and heated at reflux for 4 hr. Upon cooling, a white solid formed which was collected by filtration, washed with acetic acid, water, and dried to give 17.6 g of 2-(3,5-dichlorophenylamino)nicotinic acid.

1. temperatureheated
2. temperatureat reflux for 4 hr
3. temperatureUpon cooling
4. customa white solid formed which
5. filtrationwas collected by filtration
6. washwashed with acetic acid, water
7. customdried