4-(Bromomethyl)benzoic acid → Tert-butyl 4-(bromomethyl)benzoate

HRID 2227886Notes

Reaction equation

HRID 2227886 reaction equation
[Br:1][CH2:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=[O:8])=[CH:5][CH:4]=1.ICCCC(O[C:19]([CH3:22])([CH3:21])[CH3:20])=O>C=C(C)C>[Br:1][CH2:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([O:9][C:19]([CH3:22])([CH3:21])[CH3:20])=[O:8])=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 225994-(Bromomethyl)benzoic acidHCID 12416448tert-Butyl 4-iodobutanoate

Product 1

HCID 11414578Tert-butyl 4-(bromomethyl)benzoate

Reagents, catalysts & solvents 1

HCID 8255IsobutyleneSolvent

Procedure

4-(Bromomethyl)benzoic acid (6 g, 26 mmol) and isobutene (30 ml) were reacted by the same procedure as described in Example 3 for the preparation of tert-butyl 4-iodobutanoate and afforded the title material (2.4 g) as a pale yellow oil.

Sources & evidence

ORD record
ord-f2cdec3ec7984235ab216d57a40052f4
Source dataset
uspto-grants-2002_07
Patent number
US06414179B1

Reaction notes

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