HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 2-(Imidazol-1-yl)propiophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 2-Bromopropiophenone | HCID 16452 | — |
| Reactant | HCID 15841159 | HCID 15841159 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(Imidazol-1-yl)propiophenone | HCID 13282605 | 65% |
Reaction Steps
A mixture of 2-bromopropiophenone (21.3 g, 0.1M), imidazole (20.4 g, 0.3M), triethylethylamine (30.3 g, 0.3M) and ethyl acetate (300 ml) was refluxed overnight, cooled to room temperature and treated with water. The organic phase was separated, dried over MgSO4 and evaporated to give 2-(imidazol-1-yl)propiophenone as a viscous oil (12.95 g,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06414145B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-b59249805d4144ab9bc83d934507deee |
| Source note | uspto-grants-2002_07 |