HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → 3-Trifluoromethylsulfonyloxy-4-methoxycarbonylbenzyl triphenylphosphonium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Methyl 4-bromomethyl-2-trifluoromethylsulfonyloxybenzoate | HCID 18474595 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 3-Trifluoromethylsulfonyloxy-4-methoxycarbonylbenzyl triphenylphosphonium bromide | HCID 86758315 | 100% |
Reaction Steps
A solution of methyl 4-bromomethyl-2-trifluoromethylsulfonyloxybenzoate (23.12 g; 61 mmol) and triphenylphosphine (16 g; 61 mmol) in toluene (240 ml) was refluxed for 5 hours. The resulting solid was filtered and washed with ether to give 3-trifluoromethylsulfonyloxy-4-methoxycarbonylbenzyl triphenylphosphonium bromide. Yield=100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06414145B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-96b941c0e505453792bb3c35a018cb81 |
| Source note | uspto-grants-2002_07 |