HRID2228013

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11776

Triphenylphosphine

C18H15P

结构：COC(=O)c1ccc(CBr)cc1OS(=O)(=O)C(F)(F)F

HCID18474595

未命名化合物

PRODUCTS

生成物

结构：COC(=O)c1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1OS(=O)(=O)C(F)(F)F.[Br-]

HCID86758315

未命名化合物

收率 100%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

A solution of methyl 4-bromomethyl-2-trifluoromethylsulfonyloxybenzoate (23.12 g; 61 mmol) and triphenylphosphine (16 g; 61 mmol) in toluene (240 ml) was refluxed for 5 hours. The resulting solid was filtered and washed with ether to give 3-trifluoromethylsulfonyloxy-4-methoxycarbonylbenzyl triphenylphosphonium bromide. Yield=100%.

WORKUP

后处理

filtrationThe resulting solid was filtered
washwashed with ether

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-96b941c0e505453792bb3c35a018cb81
来源数据集: uspto-grants-2002_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06414145B1
来源说明: uspto-grants-2002_07

反应 SMILES

[Br:1][CH2:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[C:5]([O:13][S:14]([C:17]([F:20])([F:19])[F:18])(=[O:16])=[O:15])[CH:4]=1.[C:21]1([P:27]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>C1(C)C=CC=CC=1>[Br-:1].[F:18][C:17]([F:20])([F:19])[S:14]([O:13][C:5]1[CH:4]=[C:3]([CH:12]=[CH:11][C:6]=1[C:7]([O:9][CH3:10])=[O:8])[CH2:2][P+:27]([C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1)([C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)(=[O:16])=[O:15]