HRID2228021

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11776

Triphenylphosphine

C18H15P

HCID18474535

未命名化合物

PRODUCTS

生成物

结构：COC(=O)c1cc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc(-c2ccccc2)c1.[Br-]

HCID86590339

未命名化合物

收率 76%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

A solution of methyl 3-bromomethyl-5-phenylbenzoate (3.78 g; 1.23 mmol) and triphenyl phosphine (3.26 g; 1.23 mmol) in toluene (40 ml) was heated at reflux under argon atmosphere for 9 hours. The resulting solid was filtered, washed with ether and pentane to give 3-methoxycarbonyl-5-phenylbenzyl triphenylphosphonium bromide. Yield=76%.

WORKUP

后处理

temperatureat reflux under argon atmosphere for 9 hours
filtrationThe resulting solid was filtered
washwashed with ether and pentane

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-25efba040565404b86d5917b94c698c3
来源数据集: uspto-grants-2002_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06414145B1
来源说明: uspto-grants-2002_07

反应 SMILES

[Br:1][CH2:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:12]=1)[C:6]([O:8][CH3:9])=[O:7].[C:19]1([P:25]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>C1(C)C=CC=CC=1>[Br-:1].[CH3:9][O:8][C:6]([C:5]1[CH:4]=[C:3]([CH:12]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:10]=1)[CH2:2][P+:25]([C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=1)([C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1)=[O:7]