Diethyl benzylphosphonate → Benzylphosphonic Acid

HRID 2228183Notes

Reaction equation

HRID 2228183 reaction equation
[CH2:1]([P:8](=[O:15])([O:12]CC)[O:9]CC)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CO.Cl>[CH2:1]([P:8](=[O:9])([OH:15])[OH:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 14122Diethyl benzylphosphonate

Product 1

HCID 81312Benzylphosphonic AcidYield 59.2%

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 887MethanolSolvent

Procedure

A solution of diethyl benzylphosphonate (25 g) in methanol (10 ml) and concentrated hydrochloric acid (500 ml) solution was refluxed for 4 days. The mixture was cooled to room temperature, and precipitatedcrystal was collected by filtration to give benzylphosphonic acid (11.17 g) as colorless crystals.

Workup

  1. filtrationprecipitatedcrystal was collected by filtration

Sources & evidence

ORD record
ord-adb0b858a078466e884757cbe082a5a2
Source dataset
uspto-grants-2002_07
Patent number
US06413947B1

Reaction notes

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