HCID 86757228, compound → HCID 18472387, compound

Participants

Reaction Steps

In THF (25 ml) was dissolved ethyl 4-(2-methoxy-carbonyl-4-nitrophenoxy)butyrate (2.37 g, 7.61 mmol), and to the mixture was added 10% palladium-carbon (containing 50% water, 0.94 g). The mixture was subjected to catalytic reduction at room temperature for 4 hours. Insoluble materials were filtered off, and the filtrate was dried with anhydrous magnesium sulfate and concentrated under reduced pressure to give ethyl 4-(4-amino-2-methoxycarbonylphenoxy)butyrate (2.20 g). IR (KBr): 1730 cm−1.

Provenance & Evidence