3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carbonyl chloride → HCID 18470598, compound

Participants

Reaction Steps

Methyl-6-aminohexanoate hydrochloride (349 mg, 1.92 mmol) and 3-(2-chloro-6-fluorophenyl)-5-methylisoxazol-4-oyl chloride (527 mg, 1.92 mmol) were converted to 2.23 g of the title compound by the procedure of Preparation 10. (100%). EA calculated for: C18H20N2O4ClF: C, 56.48; H, 5.27; N, 7.32. Found: C, 56.66; H, 5.20; N, 7.07. MS(FD) m/z 382.2 (M+).

Provenance & Evidence