4-methoxy-N-(2-nitrophenyl)benzamide → N-(2-Aminophenyl)-4-methoxybenzamide

HRID 2228570Notes

Reaction equation

HRID 2228570 reaction equation
[CH3:1][O:2][C:3]1[CH:20]=[CH:19][C:6]([C:7]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[N+:16]([O-])=O)=[O:8])=[CH:5][CH:4]=1>C(OCC)(=O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([NH:9][C:10]2[C:11]([NH2:16])=[CH:12][CH:13]=[CH:14][CH:15]=2)=[O:8])=[CH:19][CH:20]=1

Participants

3

Reactant 1

HCID 3460424-methoxy-N-(2-nitrophenyl)benzamide

Product 1

HCID 785232N-(2-Aminophenyl)-4-methoxybenzamide

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Using a procedure similar to Example 1C except starting with N-(4-methoxybenzoyl)-2-nitroaniline in ethyl acetate, the title compound was obtained as a white solid (99%); MS(FD): 242.

Sources & evidence

ORD record
ord-7eaa53c8a2b349758d8f0f0eb5778699
Source dataset
uspto-grants-2002_07
Patent number
US06417200B1

Reaction notes

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