Pyridine → HCID 136383547, compound

HRID 2228846Notes

Reaction equation

HRID 2228846 reaction equation
[Cl-].[OH:2][NH3+:3].N1C=CC=CC=1.[CH2:10]([O:12][N:13]=[C:14]([CH2:18][C:19]([CH3:21])=[CH2:20])[C:15](=O)[CH3:16])[CH3:11]>O.CO>[CH2:10]([O:12][N:13]=[C:14]([CH2:18][C:19]([CH3:21])=[CH2:20])[C:15](=[N:3][OH:2])[CH3:16])[CH3:11]

Participants

6

Reactant 3

HCID 1049PyridineHCID 21645Hydroxylamine HClHCID 54272823HCID 54272823, compound

Product 1

HCID 136383547HCID 136383547, compoundYield 81.8%

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 962WaterSolvent

Procedure

By the method of Example 4, 211.3 g of hydroxylammonium chloride in 400 ml of water and 240 g of pyridine were reacted with 342.4 g of 5-methylhex-5-ene-2,3-dione 3-(O-ethyloxime) in 800 ml of methanol. This gave 305 g of the title compound as a yellowish solid.

Sources & evidence

ORD record
ord-eab30ebbc5d2434cb2cc7fc7156cda7b
Source dataset
uspto-grants-2002_07
Patent number
US06417388B1

Reaction notes

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