1,3-Dimethyl-2-imidazolidinone → Cyclododecanone

HRID 2228879Notes

Reaction equation

HRID 2228879 reaction equation
[O:1]1[CH:3]2[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH:2]12.[Cl-].[Li+].CN1C(=O)N(C)CC1>CN1CCCC1=O>[C:2]1(=[O:1])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

5

Reactant 3

HCID 66611,3-Dimethyl-2-imidazolidinoneHCID 924813-Oxabicyclo[10.1.0]tridecaneHCID 433294Lithium Chloride

Product 1

HCID 13246CyclododecanoneYield 94%

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Procedure

For example, German Patent No. 3,744,094 discloses an isomerization of an epoxycyclododecane in the presence of a catalyst consisting of lithium chloride in a reaction medium consisting of N-methylpyrrolidone or N,N′-dimethylethyleneurea to produce cyclododecanone with a yield of 94%.

Sources & evidence

ORD record
ord-8077f8d008f44ae6b0852c43c0644356
Source dataset
uspto-grants-2002_07
Patent number
US06417404B1

Reaction notes

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