Acetonitrile → HCID 18466529, compound

Participants

Reaction Steps

0.37 g (1 mmol) of 4-(4-Trifluoromethyl-2-methylsulfonylbenzoyl)-5-hydroxy-1-ethyl-3-methylpyrazole and 0.20 g (1.1 mmol) of p-Tos-Cl were dissolved in 20 ml of CH3CN. 0.26 g (1.8 mmol) of potassium carbonate was then added, and the mixture was stirred at room temperature for 12 h. The mixture was diluted with water and extracted with ethyl acetate. The extract was dried with MgSO4 and concentrated. This gave 4-(4-Trifluoromethyl-2-methylsulfonylbenzoyl)-l-ethyl-3-methyl-5-pyrazolyl tosylate as a wax.

Provenance & Evidence