反应详情

2.5 g (0.014 mol) of 1-phenylpropane-1,2-dione 1-(O-methyl oxime) are heated at 60° C. in 20 ml of ethanol with 1.45 g (0.029 mol) of hydrazine hydrate for 1 hour. The reaction mixture is poured onto water and extracted with diethyl ether, the organic phase is dried over sodium sulphate and the solvent is distilled off in vacuo. The residue is stirred with diethyl ether and the crystals are filtered off. 1.5 g (55.6% of theory) of 2-hydrazono-1-phenylpropan-1-one O-methyl oxime of melting point 132° C. are obtained.

1. additionThe reaction mixture is poured onto water
2. extractionextracted with diethyl ether
3. dry with materialthe organic phase is dried over sodium sulphate
4. distillationthe solvent is distilled off in vacuo
5. filtrationthe crystals are filtered off