HRID2229395

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1048

Pyrazole

C3H4N2

结构：CCCCn1c(=O)c(NC(=O)Nc2cc(CBr)ccc2C(C)(C)C)c(-c2cccc(OC)c2)c2cccnc21

HCID18467089

未命名化合物

PRODUCTS

生成物

结构：CCCCn1c(=O)c(NC(=O)Nc2cc(Cc3cc[nH]n3)ccc2C(C)(C)C)c(-c2cccc(OC)c2)c2cccnc21

HCID178448696

未命名化合物

PROCEDURE

实验过程

In the same manner as in Example 8 (b), the title compound is prepared from N-[1-butyl-4-(3-methoxyphenyl)-1,2-dihydro-2-oxo-1,8-naphthyridin-3-yl]-N′-[2-tert-butyl-5-(bromomethyl)phenyl]urea and pyrazole.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e8321ecef2e54095a680b5e69d0d6b0d
来源数据集: uspto-grants-2002_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06420381B1
来源说明: uspto-grants-2002_07

反应 SMILES

[CH2:1]([N:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][N:13]=2)[C:8]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([O:21][CH3:22])[CH:16]=2)=[C:7]([NH:23][C:24]([NH:26][C:27]2[CH:32]=[C:31]([CH2:33]Br)[CH:30]=[CH:29][C:28]=2[C:35]([CH3:38])([CH3:37])[CH3:36])=[O:25])[C:6]1=[O:39])[CH2:2][CH2:3][CH3:4].[NH:40]1[CH:44]=[CH:43][CH:42]=[N:41]1>>[CH2:1]([N:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][N:13]=2)[C:8]([C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([O:21][CH3:22])[CH:16]=2)=[C:7]([NH:23][C:24]([NH:26][C:27]2[CH:32]=[C:31]([CH2:33][C:44]3[CH:43]=[CH:42][NH:41][N:40]=3)[CH:30]=[CH:29][C:28]=2[C:35]([CH3:38])([CH3:37])[CH3:36])=[O:25])[C:6]1=[O:39])[CH2:2][CH2:3][CH3:4]