Sodium Bicarbonate → HCID 18467684, compound

Participants

Reaction Steps

[(2-Nitrophenyl)]-3,4,5-trimethoxybenzylamine (15.01 mmol, 5.0 g) in ethyl acetate (150 ml) is charged with SnCl22H2O (94.2 mmol, 7.84 ml), and is refluxed for four (4) hours. The mixture is poured into ice water (100 g), sodium bicarbonate is added to achieve pH 7. and the reaction mixture is extracted with ethyl acetate (3×50 ml). The organic layers are dried with MgSO4, are filtered and evaporated (45%)

Provenance & Evidence