HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Naphthalenesulfonyl chloride → Naphthalene-2-sulfonic Acid [4-Bromo-3-(4-methylpiperazin-1-yl)phenyl]amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Naphthalenesulfonyl chloride | HCID 7125 | — |
| Reactant | 4-Bromo-3-(4-methylpiperazin-1-yl)aniline | HCID 18180099 | — |
| Product | Naphthalene-2-sulfonic Acid [4-Bromo-3-(4-methylpiperazin-1-yl)phenyl]amide | HCID 18180049 | — |
Reaction Steps
The title compound (E120) was prepared from 4-bromo-3-(4-methylpiperazin-1-yl)benzenamine (EP 0533267A, intermediate 61) (600 mg, 2.23 mmol) and naphthalene-2-sulfonyl chloride (504 mg, 2.23 mmol) using the method of Example 1 (939 mg, 92%) MH+=460/462.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06423717B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-f5dbd87e2b0343799f8af63bc0af0c59 |
| Source note | uspto-grants-2002_07 |