Sodium Hydroxide → HCID 18466212, compound

Participants

Reaction Steps

In a 1 litre single-necked flask, the compound obtained in Step B (20 g, 6.05.10−2 mol) is heated at reflux in the presence of sodium hydroxide (20 g, 5.00.10−1 mol) and water (340 ml) for 4 hours 30 minutes. After cooling, the mixture is diluted with 150 ml of water, filtered through filter paper and acidified using concentrated hydrochloric acid in the hot state (80-90° C.); the white microspheres formed in the hot state are filtered off over a frit after complete cooling. The diacid is washed with cold water. After drying in an oven (110° C.) for one night, the title compound is dried in a desiccator in the presence of P2O5.

Provenance & Evidence