Ethyl Acetate → HCID 293025, compound

HRID 2230270Notes

Reaction equation

HRID 2230270 reaction equation
[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]=1[C:13](C)=[CH:14][C:15](O)=O.[C:19]([O:22]CC)(=[O:21])C>[Pd]>[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]=1[CH2:13][CH2:14][CH2:15][C:19]([OH:22])=[O:21]

Participants

4

Reactant 2

HCID 8857Ethyl AcetateHCID 70178239HCID 70178239, compound

Product 1

HCID 293025HCID 293025, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The compound obtained in Step A (3.4 g, 1.40.10−2 mol) is solubilised in ethyl acetate (90 ml) in the presence of 5% palladium-on-carbon. The mixture is purged with argon and placed under a hydrogen atmosphere. After 15 hours' hydrogenation, the reaction mixture is filtered over Celite, rinsed and then evaporated under reduced pressure. The title product is isolated in the form of white crystals.

Workup

  1. customThe mixture is purged with argon
  2. filtrationthe reaction mixture is filtered over Celite
  3. washrinsed
  4. customevaporated under reduced pressure

Sources & evidence

ORD record
ord-e6b0585a1cd648f7b0d6331860d9d1d2
Source dataset
uspto-grants-2002_07
Patent number
US06423870B1

Reaction notes

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