Trifluoroacetic acid → HCID 70061067, compound

HRID 2230312Notes

Reaction equation

HRID 2230312 reaction equation
[C:1]([O:5][C:6](=[O:49])[CH:7]([NH:31][C:32](=[O:48])[CH:33]([NH:38][C:39]([N:41]1[CH2:47][CH2:46][CH2:45][CH2:44][CH2:43][CH2:42]1)=[O:40])[CH2:34][CH:35]([CH3:37])[CH3:36])[CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([NH:23]C(OC(C)(C)C)=O)[CH:18]=2)=[CH:11][CH:10]=1)([CH3:4])([CH3:3])[CH3:2].FC(F)(F)C(O)=O>C(Cl)Cl>[C:1]([O:5][C:6](=[O:49])[CH:7]([NH:31][C:32](=[O:48])[CH:33]([NH:38][C:39]([N:41]1[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47]1)=[O:40])[CH2:34][CH:35]([CH3:37])[CH3:36])[CH2:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[C:19]([NH2:23])[CH:18]=2)=[CH:11][CH:10]=1)([CH3:3])([CH3:4])[CH3:2]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 70060077HCID 70060077, compound

Product 1

HCID 70061067HCID 70061067, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The product from Example 28 was dissolved in CH2Cl2 and treated with trifluoroacetic acid. The reaction mixture was stirred at room temperature for 30 minutes. The reaction mixture was concentrated and purified to give the title compound.

Workup

  1. concentrationThe reaction mixture was concentrated
  2. custompurified

Sources & evidence

ORD record
ord-5f7ab6361bdd4e32be578131fbc7efca
Source dataset
uspto-grants-2002_07
Patent number
US06423689B1

Reaction notes

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