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HRID2230440

反应详情

EQUATION

反应方程式

HRID 2230440 的结构方程式

REACTANTS

反应物

2
结构：[Br-].[K+]
HCID253877

Potassium bromide

BrK

结构：CC(C)(C)OC(=O)[C@@H]1CCCN2C(=O)CC[C@H](NC(=O)OCc3ccccc3)C(=O)N12
HCID67022104

未命名化合物

PRODUCTS

生成物

1
结构：O=C(N[C@H]1CCC(=O)N2CCC[C@@H](C(=O)O)N2C1=O)OCc1ccccc1
HCID18396550

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CO
溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

was prepared from 211d by the same method as compound 212e as colourless crystals (170 mg, 97%): mp 60-100° C.; [α]D22 −103 (c 0.10, MeOH); IR (KBr) 3341, 2947, 1728, 1675, 1531, 1456, 1422, 1339, 1272, 1248, 1221, 1174, 1122, 1056, 982, 639; 1H NMR CDCl3) δ7.35 (5H, s), 5.65 (1H, d), 5.48-5.40 (1H, m), 5.10 (2H, s), 4.76-4.57 (2H, m), 3.49-3.30 (2H, m), 2.92-2.59 (2H, m), 2.40-2.27 (2H, m), 1.97-1.67 (4H, m); MS (ES−) 374 (M−1, 100%). Accurate mass calculated for C18H22N3O6 (MH+): 376.1509. Found: 376.1483. Accurate mass calculated for C18H21N3O6Na (MNa+): 398.1328. Found: 398.1315.