HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen iodide → HCID 18464587, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen iodide | HCID 24841 | — |
| Reactant | 1-t-butoxycarbonyl-4-(1-pentyl-1H-benzimidazol-2-yl)[1,4]diazepane | HCID 21223813 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 18464587 | HCID 18464587 | — |
Reaction Steps
Hydrolyze 4-(1-pentyl-1H-benzoimidazol-2-yl)-[1,4]diazepane-1-carboxylic acid tert-butyl ester (0.70 g, 1.81 mmol) by refluxing an ethanol solution of the compound with hydroiodic acid (57%, 5 mL) as described in Example 111 to provide 2-[1,4]diazepan-1-yl-1-pentyl-1H-benzoimidazole dihydroiodide (0.85 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06423704B1 |
| Source dataset | uspto-grants-2002_07 |
| ORD ID | ord-8d73663ab474467381963149aede2850 |
| Source note | uspto-grants-2002_07 |