Sodium methanesulfinate → HCID 69983325, compound

HRID 2231124Notes

Reaction equation

HRID 2231124 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)=[C:10]([C:14]([C:16]([C:18]3[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[C:20]([Cl:26])[CH:19]=3)=[O:17])=[O:15])[CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1.[CH3:33][S:34]([O-:36])=[O:35].[Na+]>CN(C)C=O>[CH3:33][S:34]([C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([C:27]3[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=3)=[C:10]([C:14]([C:16]([C:18]3[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[C:20]([Cl:26])[CH:19]=3)=[O:17])=[O:15])[CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1)(=[O:36])=[O:35]

Participants

4

Reactant 2

HCID 2733271Sodium methanesulfinateHCID 69984439HCID 69984439, compound

Product 1

HCID 69983325HCID 69983325, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Following the procedure of Example 53, Step 4 using the benzil from Step 2 (2.8 g, 9.6 mmol) and sodium methylsulfinate (1.25 g, 12 mmol) in dimethylformamide (25 ml), there was obtained 2.3 g (70%) of the desired product: mp 163-166° C. Anal. Calc'd. for C16H13ClO5S (MW 352.79): C, 54.47; H, 3.71; S, 9.09. Found: C, 54.11; H, 3.52; S, 9.30.

Sources & evidence

ORD record
ord-e6f55572fd6645af99fa6a499dbcef6f
Source dataset
uspto-grants-2002_07
Patent number
US06426360B1

Reaction notes

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