反应详情

A solution of 14.8 grams (0.25 mole) isopropyl amine in 25 milliliters ethanol was added dropwise to a solution of ethyl bromofluoroacetate, 40 grams (0.22 mole), and 5 drops ethylene glycol in 100 milliliters ethyl alcohol at 10°-15° C. The solution was stirred at 10°-20° C. for 2 hours and was then stored at -15° C. for 3 days. At this time the solution was evaporated to leave a liquid, 41.8 grams, nD30 1.4629, identified by infrared spectroscopy as the title compound.

1. waitwas then stored at -15° C. for 3 days
2. customAt this time the solution was evaporated
3. customto leave a liquid, 41.8 grams