HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → HCID 13885086, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | Acetic acid, 2-bromo-2-fluoro-, ethyl ester | HCID 2733407 | — |
| Catalyst | Ethylene Glycol | HCID 174 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 13885086 | HCID 13885086 | — |
Reaction Steps
A solution of 14.8 grams (0.25 mole) isopropyl amine in 25 milliliters ethanol was added dropwise to a solution of ethyl bromofluoroacetate, 40 grams (0.22 mole), and 5 drops ethylene glycol in 100 milliliters ethyl alcohol at 10°-15° C. The solution was stirred at 10°-20° C. for 2 hours and was then stored at -15° C. for 3 days. At this time the solution was evaporated to leave a liquid, 41.8 grams, nD30 1.4629, identified by infrared spectroscopy as the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04781752 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-73f529b4429c466facb150e42c8c7ad4 |
| Source note | uspto-grants-1988_11 |