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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2231166Generated: November 2, 2026

Acetonitrile → Debrisoquine

https://huagongshe.com/reaction/2231166

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
Reactant1,2,3,4-TetrahydroisoquinolineHCID 7046—
ReactantAminoiminomethane-sulphonic acidHCID 3013981—
ProductDebrisoquineHCID 2966—

Reaction Steps

Tetrahydroisoquinoline (0.013 m) is treated with aminoiminomethanesulfonic acid (0.01 m) at ambient temperature. After completion of the reaction, it is diluted with acetonitrile, cooled and the solid product is collected by filtration.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04781866
Source datasetuspto-grants-1988_11
ORD IDord-b58048d523de4aaeb385546b3715860b
Source noteuspto-grants-1988_11