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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2231198Generated: November 2, 2026

Methyl iodide → HCID 21286356, compound

https://huagongshe.com/reaction/2231198

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantHCID 21286361HCID 21286361—
SolventAcetoneHCID 180—
SolventChloroformHCID 6212—
ProductHCID 21286356HCID 21286356102.1%

Reaction Steps

Methyl iodide (1.08 g) was added dropwise to a solution of 3-dimethylaminomethyl-8-(2-methoxybenzyloxy)2-methylimidazo[1,2-a]pyridine (3.42 g) in acetone (34 ml) and chloroform (10 ml) at room temperature and the mixture was stirred for 24 hours. The resulting precipitate was collected by filtration, washed with acetone, and dried in a desiccator to give 8-(2-methoxybenzyloxy)-2-methyl-3-trimethylammoniomethylimidazo[1,2-a]pyridine iodide (3.63 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04782055
Source datasetuspto-grants-1988_11
ORD IDord-985a1e89a6ee4d6eaf0135a20119598f
Source noteuspto-grants-1988_11