Ethyl formate → HCID 178494763, compound

HRID 2231247Notes

Reaction equation

HRID 2231247 reaction equation
C[O:2][CH:3]([C:5]1[NH:6][C:7]2[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=2[N:9]=1)C.C([Li])CCC.[CH:19]([O:21][CH2:22][CH3:23])=O>CCCCCC>[CH3:19][O:21][CH:22]([C:13]1[C:7]2[NH:6][C:5]([CH:3]=[O:2])=[N:9][C:8]=2[CH:10]=[CH:11][CH:12]=1)[CH3:23]

Participants

5

Reactant 3

HCID 8025Ethyl formateHCID 450784722-(1-methoxyethyl)-1H-1,3-benzodiazoleHCID 178418339Butyllithium

Product 1

HCID 178494763HCID 178494763, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Following the procedure of Example 1D, 2.36 g of 1-methoxyethylbenzimidazole, 5.15 ml of 2.6M n-butyl lithium in hexane, 1.08 ml of ethyl formate gave on work-up 1.73 g of the desired product as a yellow oil.

Sources & evidence

ORD record
ord-251e3f5d000f49628012bb8f4b3fb29c
Source dataset
uspto-grants-1988_11
Patent number
US04782050

Reaction notes

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