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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2231261Generated: November 3, 2026

Selenium Dioxide → 1-(Fluoromethyl)-1H-benzimidazole-2-carbaldehyde

https://huagongshe.com/reaction/2231261

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSelenium DioxideHCID 24007—
Reactant1-(Fluoromethyl)-2-methyl-1H-benzimidazoleHCID 21286291—
Solvent1,4-DioxaneHCID 31275—
Product1-(Fluoromethyl)-1H-benzimidazole-2-carbaldehydeHCID 1507205582.8%

Reaction Steps

Using the procedure of Example 10B and starting with 2.87 g of 1-fluoromethyl-2-methylbenzimidazole and 1.94 g of selenium dioxide in 50 ml of dioxane, 2.58 g of the desired product was isolated.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04782050
Source datasetuspto-grants-1988_11
ORD IDord-add036958017437f95a1ce9ed0077260
Source noteuspto-grants-1988_11