HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(2-Aminothiazol-4-yl)-2-butenoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Ethyl 2-(2-acetamidothiazol-4-yl)-2-butenoate | HCID 54352037 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(2-Aminothiazol-4-yl)-2-butenoic acid | HCID 53670354 | — |
Reaction Steps
8.4 parts by weight and ethyl 2-(2-acetamidothiazol-4-yl)-2-butenoate are added to a solution, warmed to 90° C., of 18.8 parts by weight of potassium hydroxide in 168 parts by volume of water. The solution is stirred for 45 minutes at the same temperature, cooled and brought to pH 3.6 with concentrated hydrochloric acid, with cooling.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04782162 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-3e6f2d7ca19a487f8f480666fa2fccb9 |
| Source note | uspto-grants-1988_11 |