反应详情

温度

100 °C

0.5 mmoles 1-acetoxy-3-methylthiopropene, pure Z isomer, and 2.5 mmoles methanol were charged into a 71 cc stainless steel bomb equipped with a glass liner and a Teflon coated stir bar. No catalyst was added. Toluene was included as an internal standard. Five milliliters of tetrahydrofuran as a solvent were also included in the reaction system. The reaction mixture was charged under argon. The bomb was sealed and carbon monoxide at a pressure of 1000 psi (at room temperature) was charged to the bomb, and the bomb was heated to 100° C. and allowed to react for 44 hours with stirring. At the termination of the reaction, the reaction products were analyzed by gas chromatography and it was found that no 2-acetoxy-4-(methylthio)butanoic acid, methyl ester was produced and that no 2-acetoxy-4-(methylthio)thiobutanoic acid, methyl ester was produced. 0.15 mmoles of acrolein and 0.11 mmoles of methyl acetate, and 0.04 mmoles of CH3SCH2CH2CHO were the only detectable products.

1. customequipped with a glass liner and a Teflon coated stir bar
2. additionNo catalyst was added
3. additionThe reaction mixture was charged under argon
4. customThe bomb was sealed
5. customto react for 44 hours
6. customAt the termination of the reaction