反应详情

A mixture of 17.3 g. (0.1 mole) of 7-methoxy-4-methylisoquinoline and 100 ml. of 48% hydrobromic acid is refluxed for sixteen hours and evaporated in vacuo. The residue is dissolved in water, neutralized with ammonium hydroxide and filtered to yield 7-hydroxy-4-methylisoquinoline.

1. additionA mixture of 17.3 g
2. customevaporated in vacuo
3. dissolutionThe residue is dissolved in water
4. filtrationfiltered