Ethanethiol → HCID 13849389, compound

HRID 2231626Notes

Reaction equation

HRID 2231626 reaction equation
[O:1]1[CH:5]=[CH:4][NH:3][C:2]1=[O:6].[CH2:7]([SH:9])[CH3:8].N(C(C)(C)C#N)=NC(C)(C)C#N>>[CH2:7]([S:9][CH:5]1[O:1][C:2](=[O:6])[NH:3][CH2:4]1)[CH3:8]

Participants

4

Reactant 3

HCID 6343Ethanethiol2×HCID 6547AzobisisobutyronitrileHCID 1861144-Oxazolin-2-one

Product 1

HCID 13849389HCID 13849389, compound

Procedure

A solution mixture comprising 3 g of 2-oxazolone, 25 ml of ethyl mercaptan and 600 mg of azobisisobutyronitrile, was reacted at 100° C. for 8 hours in an autoclave. After the completion of the reaction, excess ethyl mercaptan was distilled off, and the residue was purified by silica gel chromatography to obtain 1.6 g of 5-ethylthiooxazolidin-2-one having a melting point of from 82° to 86° C.

Workup

  1. customwas reacted at 100° C. for 8 hours in an autoclave
  2. distillationwas distilled off
  3. customthe residue was purified by silica gel chromatography

Sources & evidence

ORD record
ord-db3c3cf40cba441c8b4bbf29dabe786d
Source dataset
uspto-grants-1988_11
Patent number
US04783451

Reaction notes

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