3-Allyl-4-hydroxybenzonitrile → 4-hydroxy-3-propylBenzonitrile

HRID 2231673Notes

Reaction equation

HRID 2231673 reaction equation
[CH2:1]([C:4]1[CH:9]=[C:8]([C:10]#[N:11])[CH:7]=[CH:6][C:5]=1[OH:12])[CH:2]=[CH2:3].[H][H]>[C].[Pd].CO>[CH2:1]([C:4]1[CH:9]=[C:8]([C:10]#[N:11])[CH:7]=[CH:6][C:5]=1[OH:12])[CH2:2][CH3:3]

Participants

5

Reactant 2

HCID 2584423-Allyl-4-hydroxybenzonitrileHCID 178418361HCID 178418361, compound

Product 1

HCID 139876694-hydroxy-3-propylBenzonitrile

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 887MethanolSolvent

Procedure

A mixture of 8.15 g of 2-allyl-4-cyanophenol prepared in Reference Example 1-(ii), 1.5 g of 5% palladium-carbon and 100 ml of methanol, was stirred in a hydrogen stream for 2.5 hours. The catalyst was removed by filtration, and the solvent was distilled off from the filtrate to obtain 7.30 g of the above identified compound as a colorless oily substance.

Workup

  1. customThe catalyst was removed by filtration
  2. distillationthe solvent was distilled off from the filtrate
  3. customto obtain 7.30 g of the

Sources & evidence

ORD record
ord-b0f8e05b517f47ec9e48c258df93d05c
Source dataset
uspto-grants-1988_11
Patent number
US04783462

Reaction notes

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