HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → 2-[(5-Methyl-1H-pyrrol-2-yl)methyl]-1H-isoindole-1,3(2H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Reactant | 2-(2,5-Dioxohexyl)-1H-isoindole-1,3(2H)-dione | HCID 12348451 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-[(5-Methyl-1H-pyrrol-2-yl)methyl]-1H-isoindole-1,3(2H)-dione | HCID 13364792 | — |
Reaction Steps
36.3 g (0.14 mol) of 6-phthalimido-2,5-hexanedione, 54 g (0.7 mol) of ammonium acetate and 1 g of ammonium chloride are stirred in 700 ml of acetic acid at 80° C. for 1 hour and the mixture is worked up as in Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04785010 |
| Source dataset | uspto-grants-1988_11 |
| ORD ID | ord-1b793260a5364b4291f77f2b4e3eb9a3 |
| Source note | uspto-grants-1988_11 |