Glycine methyl ester hydrochloride → HCID 13534383, compound

Participants

Reaction Steps

9.6 g (0.03 mol) of 5-phthalimido-1-phenyl-1,4-pentanedione, 5.0 g (0.04 mol) of glycine methyl ester hydrochloride and 3.2 g (0.04 mol) of anhydrous sodium acetate are stirred in 80 ml of propionic acid at 60° C. for 20 hours. Purification is by column chromatography. Solid phase: "Silica-Woelm", particle size 0.1 to 0.2 mm; manufacturer: Messrs. Woelm, Eschwege, Germany; mobile phase: methylene chloride.

Provenance & Evidence