反应详情

6 g of the obtained N-t-butoxycarbonyl DL-homoserine was dissolved in 100 ml of methylene chloride, and 50 ml of a methylene chloride solution containing 6 g of diphenyldiazomethane was added dropwise thereto over an hour. After completion of the reaction, the reaction mixture was concentrated to a small volume, and petroleum ether was added thereto. The formed crystals were filtered off to obtain 8.6 g of N-t-butoxycarbonyl DL-homoserine benzhydryl ester.

1. additionwas added dropwise
2. waitover an hour
3. customAfter completion of the reaction
4. concentrationthe reaction mixture was concentrated to a small volume, and petroleum ether
5. additionwas added
6. filtrationThe formed crystals were filtered off