m-Chloroperbenzoic acid → 2-(4-Ethylthio-3-methylpyrid-2-yl)thiazolo[3,2-a]benzimidazole-1-oxide

HRID 2232051Notes

Reaction equation

HRID 2232051 reaction equation
[CH2:1]([S:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([C:10]2[S:21][C:13]3=[N:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[N:12]3[CH:11]=2)[C:5]=1[CH3:22])[CH3:2].ClC1C=C(C=CC=1)C(OO)=[O:28]>C(Cl)Cl>[CH2:1]([S:3][C:4]1[CH:9]=[CH:8][N:7]=[C:6]([C:10]2[S:21](=[O:28])[C:13]3=[N:14][C:15]4[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=4[N:12]3[CH:11]=2)[C:5]=1[CH3:22])[CH3:2]

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 212803642-(4-Ethylthio-3-methylpyrid-2-yl)-thiazolo[3,2-a]benzimidazole

Product 1

HCID 212803682-(4-Ethylthio-3-methylpyrid-2-yl)thiazolo[3,2-a]benzimidazole-1-oxide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 2-(4-ethylthio-3-methylpyrid-2-yl)-thiazolo[3,2-a]benzimidazole (0.01 mole) is dissolved in CH2Cl2 solution (100 ml) at 0° C. and treated with m-chloroperoxybenzoic acid (0.01 mole) for 0.5 hours. The solution is then washed with sodium carbonate solution and dried (MgSO4). Purification by chromatography on silica gives the title compound.

Workup

  1. washThe solution is then washed with sodium carbonate solution
  2. dry with materialdried (MgSO4)
  3. customPurification by chromatography on silica

Sources & evidence

ORD record
ord-ff5fc0b08a0d45b8bf72e1e359b1cd36
Source dataset
uspto-grants-1988_11
Patent number
US04786636

Reaction notes

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