反应详情

To 1-benzyl-3-azidomethyl-4-chloropyrrolidine (3.0 g) are added ethanol (50 ml) and 10 % palladium carbon (0.5 g), and catalytic reduction is carried out under a hydrogen pressure of from 3 to 4 atm. at 50° C. After removing the catalyst from the mixture by a filteration, the resultant is concentrated to give 3-aminomethyl -1-benzyl-4-chloropyrrolidine (2.96g) as an oil.

1. customat 50° C
2. customAfter removing the catalyst from the mixture by a filteration
3. concentrationthe resultant is concentrated