HCID 13959885, compound → 3-Aminomethyl-1-benzyl-4-chloropyrrolidine

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Reaction Steps

To 1-benzyl-3-azidomethyl-4-chloropyrrolidine (3.0 g) are added ethanol (50 ml) and 10 % palladium carbon (0.5 g), and catalytic reduction is carried out under a hydrogen pressure of from 3 to 4 atm. at 50° C. After removing the catalyst from the mixture by a filteration, the resultant is concentrated to give 3-aminomethyl -1-benzyl-4-chloropyrrolidine (2.96g) as an oil.

Provenance & Evidence